18-(tert-Butoxy)-18-oxooctadecanoic acid
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Used as a side chain component in peptide synthesis, 18-(tert-Butoxy)-18-oxooctadecanoic acid (CAS No. 843666-40-0, molecular formula C₂₂H₄₂O₄) is a white solid containing a tert-butyl ester group that increases its hydrophobicity. This property makes it especially useful in the development of lipid-modified peptides, where enhanced membrane interaction or prolonged half-life is desired. It’s widely used in the synthesis of GLP-1 receptor agonists such as Semaglutide and Tirzepatide, contributing to the design of stable, long-acting structures. The compound is packaged in 25 kg fiber drums and should be stored in sealed containers at room temperature, in a dry environment to preserve its integrity.
- CAS No.: 843666-40-0
- Molecular Formula: C₂₂H₄₂O₄
- Purity: 99% min
- Appearance White to white-like solid
- Molecular Weight 370.6 g/mol
- Density 0.950 ± 0.06 g/cm³ (predicted)
- Boiling Point 470.7 ± 18.0 °C (predicted)
- Melting Point 68 °C
- Flash Point N/A
- Packaging 25 kg/fibre drum
- Customs Code 2917198090
- Storage Conditions Store in a dry, sealed container at room temperature
- Product Name
- 18-(tert-butoxy)-18-oxooctadecanoic acid;
- Octadecanedioic acid mono-tert-butyl ester;
- 18-[(2-methylpropan-2-yl)oxy]-18-oxooctadecanoic acid;
- Octadecanedioic Acid Mono(1,1-dimethylethyl) Ester
- Monthly Production Capacity 500 kg/month
- Applications Side chain intermediate for Semaglutide and Tirzepatide synthesis

