H-Glu-OtBu

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H-Glu-OtBu (CAS No. 45120-30-7, C₉H₁₇NO₄) is a white powder used as a protected derivative of L-glutamic acid in peptide synthesis. It features a tert-butyl ester group that allows selective side chain protection, making it suitable for solid-phase synthesis protocols. This compound is commonly applied in the production of active peptides and pharmaceutical intermediates, including GLP-1 analogs like Semaglutide and Tirzepatide. It comes packaged in 25 kg fibre drums and should be stored sealed, in a cool and dry environment to preserve stability.

CAS No.: 45120-30-7
Molecular Formula: C₉H₁₇NO₄
Purity: 98% min

Appearance White powder
Molecular Weight 203.24 g/mol
Density 1.1 ± 0.1 g/cm³
Boiling Point 326.8 ± 32.0 °C at 760 mmHg
Melting Point 140 °C
Flash Point 151.5 ± 25.1 °C
Packaging 25 kg per fiber drum
Customs Code 2922509090
Storage Conditions Store sealed, in a cool and dry place

Product Name
1. H-Glu-OtBu;
2. (S)-4-Amino-5-(tert-butoxy)-5-oxopentanoic acid;
3. 1-tert-Butyl L-glutamate;
4. L-Glutamic acid a-tert-butyl ester;
5. (4S)-4-amino-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid;
6. L-Glutamic acid alpha-tert-butyl ester.
Monthly Production Capacity 300 kg/month
Applications Side chain intermediate for Semaglutide, Tirzepatide, and peptide API synthesis

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