Fmoc-Lys(dde)-OH

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Fmoc-Lys(dde)-OH (CAS No. 150629-67-7) is commonly chosen in peptide synthesis protocols where ε-amino group protection must remain stable under basic conditions but be removable without affecting Fmoc. The Dde group meets that requirement, offering mild cleavage with hydrazine while preserving other functionalities. Its use supports the stepwise introduction of modifications in complex peptides, including GLP-1 analogs.

CAS No.: 150629-67-7
Molecular Formula: C₃₁H₃₆N₂O₆
Purity: 99% min

Appearance White solid
Molecular Weight 532.6 g/mol
Density 1.2 ± 0.1 g/cm³
Boiling Point 750.1 ± 60.0 °C at 760 mmHg
Melting Point ~80 °C (decomposition)
Flash Point 407.5 ± 32.9 °C
Packaging 25 kg / fibre drum
Customs Code 29242970
Storage Conditions Store sealed and dry at below −20 °C to ensure long-term stability

Product Name
1. Fmoc-Lys(Dde)-OH;
2. (2S)-6-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethylamino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid;
3. L-Lysine, N₆-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]-N₂-[(9H-fluoren-9-ylmethoxy)carbonyl]-;
4. (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[1-(2-hydroxy-4,4-dimethyl-6-oxocyclohexen-1-yl)ethylideneamino]hexanoic acid;
5. N-alpha-Fmoc-N-epsilon-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]-L-lysine
Production Capacity 1 ton/month
Applications Raw material for GLP-1 peptide synthesis, polypeptides

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