Fmoc-L-Glu(OtBu)-OH

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Fmoc-L-Glu(OtBu)-OH (CAS No. 71989-18-9) is a protected glutamic acid derivative used in solid-phase peptide synthesis. The Fmoc group on the α-amino terminus and the tert-butyl ester on the side-chain carboxyl allow for controlled, stepwise coupling. This structure makes it suitable for synthesizing complex peptides such as Semaglutide and Tirzepatide. With a molecular formula of C₂₄H₂₇NO₆ and a molecular weight of 425.5 g/mol, it is provided as a white powder with 99% min purity and should be stored sealed in a cool, dry place.

CAS No.: 71989-18-9
Molecular Formula: C₂₄H₂₇NO₆
Purity: 99% min

Appearance White powder
Molecular Weight 425.5 g/mol
Density 1.2 ± 0.1 g/cm³
Boiling Point 633.5 ± 55.0 °C at 760 mmHg
Melting Point 83–90 °C
Flash Point 337.0 ± 31.5 °C
Packaging 25 kg / fibre drum
Storage Conditions Store in a sealed, dry, cool place
Customs Code 29242970
Production Capacity 3 ton/month
Applications Raw material for GLP-1 peptides, polypeptides, Semaglutide, and Tirzepatide

Product Name
1. Fmoc-Glu(OtBu)-OH;
2. Fmoc-L-glutamic acid 5-tert-butyl ester;
3. (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid;
4. (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid;
5. N-Fmoc-L-glutamic acid 5-tert-butyl ester;
6. (2S)-5-(tert-butoxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-oxopentanoic acid;
7. L-glutamic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 5-(1,1-dimethylethyl) ester

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