Fmoc-His-Aib-OH

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With a structure designed to improve peptide chain stability, Fmoc-His-Aib-OH (CAS No. 1446013-07-5, molecular formula C₂₅H₂₆N₄O₅) is a white powder intermediate commonly used in the synthesis of Semaglutide. The combination of Fmoc-protected histidine and Aib allows for efficient incorporation into complex peptide sequences, minimizing steric interference. This compound has a molecular weight of 462.5 g/mol and is available in 25 kg fibre drums for convenient handling and storage.

CAS No.: 1446013-07-5
Molecular Formula: C₂₅H₂₆N₄O₅
Purity: 99% min

Appearance White powder
Molecular Weight 462.5 g/mol
Density 1.3 ± 0.1 g/cm³ (Predicted)
Boiling Point 838.1 ± 65.0 °C at 760 mmHg (Predicted)
Melting Point N/A
Flash Point N/A
Packaging 25 kg/fibre drum
Storage Conditions Store in a dry, sealed container at 2–8 °C
Production Volume per Batch 100 kg
Production Cycle 12 days

Product Name
1. Fmoc-His-Aib-OH Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-histidyl-2-methyl-;
2. 2-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(1H-imidazol-5-yl)propanamido]-2-methylpropanoic acid
Production capacity 1000 kg/month
Applications Intermediate for Semaglutide peptide synthesis

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