Fmoc-L-Ile-OH
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Valued for its branched aliphatic side chain, Fmoc-L-Ile-OH (CAS No. 71989-23-6) plays a key role in the synthesis of hydrophobic segments in peptides. It’s widely used in Fmoc-SPPS for GLP-1 analogs such as Semaglutide and Tirzepatide. This protected isoleucine ensures reliable coupling efficiency and high structural fidelity throughout peptide chain assembly.
- CAS No.: 71989-23-6
- Molecular Formula: C₂₁H₂₃NO₄
- Purity: 99% min
- Appearance White to off-white crystalline powder
- Molecular Weight 353.4 g/mol
- Density 1.2 ± 0.1 g/cm³
- Boiling Point 559.8 ± 33.0 °C at 760 mmHg
- Melting Point 145–147 °C (lit.)
- Flash Point 292.4 ± 25.4 °C
- Packaging 25 kg / fibre drum
- Customs Code 29242970
- Storage Conditions Store tightly sealed at 2–8 °C in a clean, dry environment to maintain product integrity
- Product Name
- Fmoc-Ile-OH;
- Fmoc-L-isoleucine;
- N-Fmoc-L-isoleucine;
- Fmoc-L-Ile-OH;
- N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-isoleucine;
- N-(9-Fluorenylmethoxycarbonyl)-L-isoleucine;
- Fmoc-D-Ile-OH;
- (2S,3S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylpentanoic acid
- Production Capacity 5 ton/month
- Applications Raw material for GLP-1 peptide synthesis, polypeptides, Semaglutide, and Tirzepatide

