Fmoc-Pro-Pro-OH

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Fmoc-Pro-Pro-OH (CAS No. 129223-22-9) is widely used to introduce conformational constraints in peptide chains. This dipeptide, made of two L-proline residues and protected with an Fmoc group, promotes rigid secondary structures due to proline’s cyclic backbone. It's especially useful in the synthesis of GLP-1 analogs and other peptides that require defined turns or restricted flexibility during folding and receptor interaction.

CAS No.: 129223-22-9
Molecular Formula: C₂₅H₂₆N₂O₅
Purity: 99% min

Appearance White solid
Molecular Weight 434.5 g/mol
Density 1.4 ± 0.1 g/cm³
Boiling Point 677.7 ± 55.0 °C at 760 mmHg
Melting Point N/A
Flash Point 363.7 ± 31.5 °C
Packaging 25 kg / fibre drum
Customs Code 2933998090
Storage Conditions Store sealed in a dry container at 2–8 °C

Product Name
1. Fmoc-Pro-Pro-OH;
2. (S)-1-((S)-1-(((9H-fluoren-9-yl)methoxy)carbonyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxylic acid;
3. L-Proline, 1-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-prolyl-;
4. (2S)-1-[(2S)-1-(9H-fluoren-9-ylmethoxycarbonyl)pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acid
Production Capacity 1 ton/month
Applications Raw material for GLP-1 peptide synthesis, polypeptides

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