Fmoc-L-Tyr(tBu)-OH

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Fmoc-L-Tyr(tBu)-OH (CAS No. 71989-38-3) is a protected tyrosine used in Fmoc-SPPS. It features an Fmoc group at the α-amino position and a tert-butyl group on the phenolic hydroxyl, which prevents undesired side reactions during synthesis. This derivative is commonly applied in the preparation of GLP-1 peptides such as Semaglutide and Tirzepatide.

• CAS No.: 71989-38-3
• Molecular Formula: C₂₈H₂₉NO₅
• Purity: 99% min

• Appearance White powder
• Molecular Weight 459.5 g/mol
• Density 1.3 ± 0.1 g/cm³
• Boiling Point N/A
• Melting Point 86–90 °C
• Flash Point N/A
• Packaging 25 kg / fibre drum
• Customs Code 29242970
• Storage Conditions Store at 2–8 °C in a sealed container protected from light and moisture

• Product Name
  1. Fmoc-Tyr(tBu)-OH;
  2. Fmoc-O-tert-butyl-L-tyrosine;
  3. Fmoc-L-Tyr(tBu)-OH;
  4. Fmoc-Tyr(t-Bu)-OH;
  5. (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(tert-butoxy)phenyl)propanoic acid;
  6. N-Fmoc-O-tert-butyl-L-tyrosine;
  7. Nalpha-Fmoc-O-tert-butyl-L-tyrosine
• Production Capacity 3 ton/month
• Applications Raw material for GLP-1 peptide synthesis, polypeptides, Semaglutide, and Tirzepatide