Fmoc-L-Ser(tBu)-OH
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Fmoc-L-Ser(tBu)-OH (CAS No. 71989-33-8) is a side-chain protected serine derivative frequently used in solid-phase peptide synthesis. The Fmoc group protects the amino functionality, while the tert-butyl group ensures stability of the hydroxyl side chain during elongation. Thanks to its compatibility with standard synthesis protocols, it's particularly suitable for assembling GLP-1 analogues such as Semaglutide and Tirzepatide. This compound is available as a white crystalline powder, with 99% min purity, molecular formula C₂₂H₂₅NO₅, and molecular weight of 383.4 g/mol.
- CAS No.: 71989-33-8
- Molecular Formula: C₂₂H₂₅NO₅
- Purity: 99% min
- Appearance White crystalline powder
- Molecular Weight 383.4 g/mol
- Density 1.2 ± 0.1 g/cm³
- Boiling Point 578.6 ± 50.0 °C at 760 mmHg
- Melting Point 130.5–135.5 °C (lit.)
- Flash Point 303.7 ± 30.1 °C
- Packaging 25 kg / fibre drum
- Storage Conditions 2–8 °C
- Customs Code 29242990
- Product Name
- Fmoc-Ser(tBu)-OH;
- Fmoc-O-tert-butyl-L-serine;
- Fmoc-L-Ser(tBu)-OH
- Production Capacity 3 ton/month
- Applications GLP-1 peptide synthesis, polypeptide APIs, Semaglutide and Tirzepatide production

