Fmoc-Lys(Ivdde)-OH

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The structure of Fmoc-Lys(Ivdde)-OH (CAS No. 204777-78-6) includes an Fmoc group on the α-amino and an Ivdde group on the ε-amino side chain. This configuration allows selective deprotection steps, as the Ivdde group can be removed with hydrazine while remaining stable under standard Fmoc conditions. It is commonly used in applications that require orthogonal protection strategies, such as branched or multifunctional peptide synthesis.

CAS No.: 204777-78-6
Molecular Formula: C₃₄H₄₂N₂O₆
Purity: 99% min

Appearance White powder
Molecular Weight 574.7 g/mol
Density 1.2 ± 0.1 g/cm³
Boiling Point 765.6 ± 60.0 °C at 760 mmHg
Melting Point N/A
Flash Point 416.8 ± 32.9 °C
Packaging 25 kg / fibre drum
Customs Code 29242970
Storage Conditions Store at 2–8 °C in sealed, dry conditions
Production Capacity 1 ton/month

Product Name
1. Fmoc-Lys(IvDde)-OH;
2. Fmoc-L-Lys(Ivdde)-OH;
3. Fmoc-Lys(Ddiv)-OH;
4. (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl)amino)hexanoic acid;
5. L-Lysine,N₆-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]-N₂-[(9H-fluoren-9-ylmethoxy)carbonyl]-;
6. (2S)-6-[[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid
Applications Raw material for GLP-1 peptide synthesis, polypeptides

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