Fmoc-L-Leu-OH
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Fmoc-L-Leu-OH (CAS No. 35661-60-0) is a protected leucine derivative widely used in peptide synthesis. Thanks to its Fmoc-protected amino group, it allows for selective chain elongation in solid-phase synthesis. This compound plays an important role in the preparation of GLP-1 peptide drugs, including Semaglutide and Tirzepatide.
- CAS No.: 35661-60-0
- Molecular Formula: C₂₁H₂₃NO₄
- Purity: 99% min
- Appearance White solid
- Molecular Weight 353.4 g/mol
- Density 1.2 ± 0.1 g/cm³
- Boiling Point 559.8 ± 33.0 °C at 760 mmHg
- Melting Point 152–156 °C (lit.)
- Flash Point 292.4 ± 25.4 °C
- Packaging 25 kg / fibre drum
- Storage Conditions Keep sealed, cool and dry
- Customs Code 29242970
- Production Capacity 5 ton/month
- Product Name
- Fmoc-L-leucine;
- Fmoc-Leu-OH;
- Fmoc-L-Leu-OH;
- N-Fmoc-L-leucine;
- N-(9-fluorenylmethoxycarbonyl)-L-leucine;
- fmoc-leucine;
- N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-leucine;
- (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid;
- n-(fluorenyl-9-methoxycarbonyl)leucine
- Applications Raw material for GLP-1 peptide synthesis, polypeptides, Semaglutide, and Tirzepatide

